OCRL antibody (N-Term)

Catalog No. ABIN375369

The Rabbit Polyclonal anti-OCRL antibody (ABIN375369) specifically detects OCRL in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for OCRL antibody (N-Term) (ABIN375369)

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OCRL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-OCRL Antibody

Binding Specificity: N-Term

Specificity: Reacts with human 104 kDa OCRL protein

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Cross reacts with proteins from mouse and other species.

Purification: Antiserum

Immunogen: Synthetic peptide derived from Nter domain of human OCRL protein

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/500 - WB : 1/500 to 1/2 000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for OCRL

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Alternative Name: Inositol Polyphosphate 5-Phosphatase OCRL-1

Background: Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly.

UniProt: Q01968

Pathways: Inositol Metabolic Process