CD11c antibody (Biotin)

Catalog No. ABIN376017

The Biotin-conjugated Mouse Monoclonal anti-CD11c antibody (Clone 3-9) (ABIN376017) specifically detects CD11c in FACS. The antibody is reactive with Human samples.

Quick Overview for CD11c antibody (Biotin) (ABIN376017)

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD11c antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: 3-9

Product Details anti-CD11c Antibody (Biotin)

Specificity: Human/Rhesus/Cynomolgus CD11c, Mr 150 kDa

Characteristics: Mouse Anti-Human CD11c-BIOT

Purification: Purified

Immunogen: Rheumatoid synovial cells and human monocytes

Isotype: IgG1

Application Details

Application Notes:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, PACBLU, AF488, AF647, and AF700 conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Restrictions: For Research Use only

Handling

Buffer: 100 tests in 1.0 mL of PBS/Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for CD11c

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Alternative Name: CD11c

Background: CD11c is a 150 kDa adhesion glycoprotein that associates with β 2 integrin to form the CD11c/CD18 heterodimer that binds CD54 (ICAM-1) and fibrinogen. It is expressed on NK cells, a subset of B and T cells, granulocytes, monocytes, and macrophages. It functions in cytotoxic T cell killing and in neutrophil and monocyte adhesion to endothelium.

Pathways: Complement System, Activated T Cell Proliferation, Integrin Complex