Goat anti-Human IgG Antibody (PE)

Catalog No. ABIN376511

Quick Overview for Goat anti-Human IgG Antibody (PE) (ABIN376511)

Target: IgG

Fragment: F(ab')2 fragment

Clonality: Polyclonal

Conjugate: PE

Application: Flow Cytometry (FACS), FLISA

Isotype: IgG

Product Details

Reactivity: Human

Host: Goat

Purpose: Goat F(ab')2 Anti-Human IgG-PE

Specificity: Reacts with the heavy chain of human IgG

Characteristics: Goat F(ab')2 Anti-Human IgG-PE antibody for use in flow cytometry assays.

Purification: Purified by affinity chromatography on human IgG covalently linked to agarose, cross-adsorbed against human IgM and IgA for minimal reactivity

Immunogen: Human IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Pepsin digest of Goat Anti-Human IgG (SouthernBiotech Cat. No. 2040) - Pooled antisera from goats hyperimmunized with human IgG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Phosphate buffered saline containing < 0.1 % sodium azide and a stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C

References

Brandsma, Bondza, Evers, Koutstaal, Nederend, Jansen, Rösner, Valerius, Leusen, Ten Broeke: "Potent Fc Receptor Signaling by IgA Leads to Superior Killing of Cancer Cells by Neutrophils Compared to IgG." in: Frontiers in immunology, Vol. 10, pp. 704, (2019) (PubMed).

Cheng, Yang, Chen, Hsu, Jou, Hsieh, Tseng: "CLEC9A modulates macrophage-mediated neutrophil recruitment in response to heat-killed Mycobacterium tuberculosis H37Ra." in: PLoS ONE, Vol. 12, Issue 10, pp. e0186780, (2017) (PubMed).

Trinklein, Pham, Schellenberger, Buelow, Boudreau, Choudhry, Clarke, Dang, Harris, Iyer, Jorgensen, Pratap, Rangaswamy, Ugamraj, Vafa, Wiita, van Schooten, Buelow, Force Aldred: "Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies." in: mAbs, Vol. 11, Issue 4, pp. 639-652 (PubMed).

Target Details

Target: IgG

Target Type: Antibody

Background: Optional[Description]: Goat F(ab')2 Anti-Human IgG-PE