CD94 antibody

Catalog No. ABIN376891

Product Details anti-CD94 Antibody

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD94 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Mouse CD94

Characteristics: Rat Anti-Mouse CD94-UNLB

Purification: Purified

Immunogen: CHO cells transfected with the B6 allele of CD94

Clone: 18d3

Isotype: IgG2a

Application Details

Application Notes:

• Applications: FC - Quality tested
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugate 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Preservative: Without preservative

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for CD94

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Alternative Name: CD94 (KLRD1 Products)

Synonyms: CD94 antibody, CD94-B antibody, Cd94 antibody, killer cell lectin like receptor D1 antibody, killer cell lectin-like receptor subfamily D, member 1 antibody, killer cell lectin-like receptor, subfamily D, member 1 antibody, KLRD1 antibody, Klrd1 antibody

Background: CD94 is expressed on the surface of NK cells, NK T cells and some memory phenotype CD8 + cells. When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1 b and results in a CD94 high population by flow cytometry. Approximately half of NK cells do not express NKG2A, C or E, these cells express CD94 on the surface in a form that does not bind Qa-1 b and is believed to be nonfunctional, producing a CD94 low population by flow cytometry. CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.