Thymidine Phosphorylase antibody

Catalog No. ABIN379032

The Mouse Monoclonal anti-Thymidine Phosphorylase antibody has been validated for WB and IHC. It is suitable to detect Thymidine Phosphorylase in samples from Human.

Quick Overview for Thymidine Phosphorylase antibody (ABIN379032)

Target: Thymidine Phosphorylase (TYMP)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Thymidine Phosphorylase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: P-GF-44C

Product Details anti-Thymidine Phosphorylase Antibody

Specificity: Is specific to a 55 kD protein known as platelet- derived endothelial growth factor (PD-ECGF), similar to thymidine phosphorylase (TP). High levels of TP/PD-ECGF are observed in cancer patients. High intra-cellular levels of TP/PD- ECGF are associated with increased chemo sensitivity to such antimetabolites.

Purification: Ig fraction

Immunogen: BALB/C mice were injected with a recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein.

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, WB (1:50 - 1:100)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Buffer contains: 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for Thymidine Phosphorylase

Target: Thymidine Phosphorylase (TYMP)

Alternative Name: TP / Thymidine Phosphorylase

Background: Name/Gene ID: TYMP

Synonyms: TYMP, ECGF1, HPD-ECGF, MEDPS1, MNGIE, MTDPS1, PD-ECGF, Thymidine phosphorylase, PDECGF, ECGF, Gliostatin, TdRPase, TP

Gene ID: 1890

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2