Metalloproteinase Inhibitor 2 (TIMP2) (N-Term) antibody

Details for Product No. ABIN379072
Antigen
  • CSC-21K
  • DDC8
  • TIMP-2
  • D11Bwg1104e
  • Timp-2
  • etID32613.12
  • fa96h09
  • timp2
  • wu:fa96h09
  • zgc:136726
  • TIMP metallopeptidase inhibitor 2
  • tissue inhibitor of metalloproteinase 2
  • TIMP metallopeptidase inhibitor 2a
  • TIMP2
  • Timp2
  • timp2a
Epitope
N-Term
39
32
25
16
15
13
7
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Guinea Pig, Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
273
136
133
50
47
45
45
16
15
14
12
9
7
4
2
1
1
1
Host
Mouse
152
125
15
6
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
21
8
7
5
5
5
5
5
5
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
223
117
96
85
46
44
15
14
13
10
10
6
6
2
2
2
1
Options
Immunogen BALB/C mice were injected with a synthetic peptide from the N-terminal region of human TIMP-2.

Type of Immunogen: Synthetic peptide
Clone 3A4
Isotype IgG2a, kappa
Specificity Is specific to 21 kD protein known as TIMP-2. TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family. TIMPs are of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kD Type IV collagenase (MMP-2) and active form of 92 kD Type IV collagenase (MMP-9). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. This antibody cross reacts with mouse, rat, rabbit, cow and Guinea pig.
Purification Ig fraction
Antigen
Alternative Name TIMP2 (TIMP2 Antibody Abstract)
Background Name/Gene ID: TIMP2

Synonyms: TIMP2, Metalloproteinase inhibitor 2, TIMP-2, CSC-21K
Gene ID 7077
Pathways cAMP Metabolic Process
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Target Species of Antibody: Human

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Buffer contains: 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze.
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