TIMP2 antibody (N-Term)

Catalog No. ABIN379072

Product Details anti-TIMP2 Antibody

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This TIMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Is specific to 21 kD protein known as TIMP-2. TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family. TIMPs are of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kD Type IV collagenase (MMP-2) and active form of 92 kD Type IV collagenase (MMP-9). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. This antibody cross reacts with mouse, rat, rabbit, cow and Guinea pig.

Purification: Ig fraction

Immunogen: BALB/C mice were injected with a synthetic peptide from the N-terminal region of human TIMP-2.

Type of Immunogen: Synthetic peptide

Clone: 3A4

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Buffer contains: 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Alternative Name: TIMP2 (TIMP2 Products)

Background: Name/Gene ID: TIMP2

Synonyms: TIMP2, Metalloproteinase inhibitor 2, TIMP-2, CSC-21K

Gene ID: 7077

Pathways: cAMP Metabolic Process