Caspase 3 antibody (CASP3)

Details for Product anti-CASP3 Antibody No. ABIN379634
Target
  • CPP32
  • CPP32B
  • SCA-1
  • A830040C14Rik
  • AC-3
  • Apopain
  • CC3
  • Caspase-3
  • Lice
  • Yama
  • mldy
  • xcpp32
  • casp3
  • zgc:100890
  • CASP-3
  • caspase-3
  • caspase 3
  • caspase 3 S homeolog
  • caspase 3, apoptosis-related cysteine peptidase a
  • caspase 3, apoptosis-related cysteine peptidase
  • CASP3
  • Casp3
  • casp3.S
  • casp3a
Reactivity
Cow, Dog, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
310
190
167
36
20
17
17
17
16
9
9
9
5
4
4
3
2
2
1
Host
Rabbit
305
51
9
2
2
Clonality
Polyclonal
Conjugate
This Caspase 3 antibody is un-conjugated
28
21
14
9
8
8
8
8
7
7
7
7
2
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
248
148
133
70
47
35
34
34
29
29
14
12
9
9
5
2
1
1
1
Options
Immunogen Recombinant full-length human Caspase 3 protein.

Type of Immunogen: Recombinant protein
Specificity Reacts with active form of caspase 3 (17 kD protein). Caspase 3 is a member of the interleukin-1 beta-converting enzyme family. Caspase 3 is though to be associated with induction of apoptosis. Caspase 3 is synthesized as inactive 32 kD proenzyme and is processed during apoptosis generating two subunits of 17 kD and 12 kD. Caspase 3 stains the epithelial cells of skin, renal proximal tubules and collecting ducts. This antibody cross reacts with mouse, rat, monkey, rabbit, hamster, cow, sheep, pig and dog.
Purification Ig fraction
Target
Alternative Name CASP3 / Caspase 3 (CASP3 Antibody Abstract)
Background Name/Gene ID: CASP3
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP3, Apopain, CASP-3, Caspase-3, CPP32B, CPP32, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Procaspase3, Caspase 3, CPP-32, PARP cleavage protease, Protein Yama
Gene ID 836
Pathways Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
Application Notes Approved: IHC, IHC-P (1:50 - 1:100)

Usage: FFPE tissue sections require high temperature antigen unmasking with 10 mM citrate buffer,  pH 6.0 prior to immunostaining.
Comment

Target Species of Antibody: Human

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Antiserum, sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze.