PTGS2 antibody (C-Term)

Catalog No. ABIN379656

The Rabbit Polyclonal anti-PTGS2 antibody has been validated for IHC. It is suitable to detect PTGS2 in samples from Human, Mouse and Rat.

Quick Overview for PTGS2 antibody (C-Term) (ABIN379656)

Target: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGS2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-PTGS2 Antibody

Binding Specificity: C-Term

Specificity: Reacts with a 70 kD protein. COX2 (Cyclooxygenase-2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters and cytokines that induce its expression. COX2 expression markedly increased in 85-90 % of human colorectal adenocarcinoma whereas COX1 levels remain unchanged. This antibody cross reacts with mouse and rat.

Purification: Ig fraction

Immunogen: Recombinant protein corresponding to c-terminus of rat COX2.

Type of Immunogen: Recombinant protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Buffer contains: 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for PTGS2

Target: PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))

Alternative Name: PTGS2 / COX2 / COX-2

Background: Name/Gene ID: PTGS2

Synonyms: PTGS2, COX-2, Cyclooxygenase-2, COX2, Cyclooxygenase 2b, HCox-2, GRIPGHS, PGH synthase 2, PGHS-2, PHS II, PHS-2, Prostaglandin H2 synthase 2, PGG/HS, Prostaglandin G/H synthase 2

Gene ID: 5743

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation