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c-MET antibody (Met Proto-Oncogene) (pTyr1234) Primary Antibody

MET Reactivity: Human, Mouse WB Host: Mouse Monoclonal 6AT1877 unconjugated
Catalog No. ABIN387740
$434.50
Plus shipping costs $45.00
400 μL ABIN387740
400 μL ABIN387740
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days
  • Target
    c-MET (MET)
    Binding Specificity
    • 42
    • 42
    • 29
    • 23
    • 18
    • 16
    • 15
    • 13
    • 11
    • 10
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1234, pTyr1235
    Reactivity
    • 290
    • 173
    • 120
    • 11
    • 9
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 243
    • 54
    • 3
    • 2
    Mouse
    Clonality
    • 229
    • 73
    Monoclonal
    Conjugate
    • 151
    • 20
    • 15
    • 12
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    This c-MET antibody is un-conjugated
    Application
    • 178
    • 121
    • 64
    • 56
    • 49
    • 27
    • 26
    • 26
    • 15
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This monoclonal antibody is generated from mice immunized with a KLH conjugated synthetic peptide corresponding to sequences in Tyr1234/1235 region of human Met and residues both Tyr1234 and Tyr1235 are phosphorylated.
    Clone
    6AT1877
    Isotype
    IgG1
  • Application Notes
    WB: 1:100~500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    c-MET (MET)
    Alternative Name
    MET/HGFR (MET Antibody Abstract)
    Synonyms
    AUTS9, HGFR, RCCP2, c-Met, AI838057, HGF, Par4, Hgfr, c-met, MET, C-MET, met, met-A, MET proto-oncogene, receptor tyrosine kinase, met proto-oncogene, MET proto-oncogene, receptor tyrosine kinase L homeolog, MET, Met, met.L
    Background
    The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    155541
    Gene ID
    4233
    NCBI Accession
    NP_000236, NP_001120972
    UniProt
    P08581
    Pathways
    RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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