FLT4 antibody

Catalog No. ABIN387818

Product Details anti-FLT4 Antibody

Target: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FLT4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged VGFR3 protein(Fragment) was used to produced this monoclonal antibody.

Clone: 44CT92-4-4

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-FLT4 antibody (ABIN387818)

Hong, Chen, Chiou, Chiu, Yang, Hsiao, Chang, Yu, Hung, Hsu, Shiah, Hsu, Su: "miR326 maturation is crucial for VEGF-C-driven cortactin expression and esophageal cancer progression." in: Cancer research, Vol. 74, Issue 21, pp. 6280-90, (2014) (PubMed).

Target Details for FLT4

Target: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Alternative Name: VGFR3 (FLT4 Products)

Background: This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.

Molecular Weight: 152757

Gene ID: 2324

NCBI Accession: NP_002011, NP_891555

UniProt: P35916

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling