Histone Deacetylase 9 (HDAC9) (AA 503-533), (C-Term) antibody

Details for Product No. ABIN387961, Supplier: Log in to see
Antigen
  • HD7
  • HD7b
  • HD9
  • HDAC
  • HDAC7
  • HDAC7B
  • HDAC9B
  • HDAC9FL
  • HDRP
  • MITR
  • AV022454
  • D030072B18Rik
  • HD7B
  • Hdac7b
  • Mitr
  • mKIAA0744
  • hdac9
  • zgc:73392
  • TWIST
  • HDAC9
  • DKFZp459E171
  • HDA09
  • HISTONE DEACETYLASE
  • histone deacetylase 9
  • RGD1310748
  • RGD1563092
  • hdac9-A
  • histone deacetylase 9
  • histone deacetylase 9b
  • histone deacetylase 9 S homeolog
  • HDAC9
  • Hdac9
  • hdac9b
  • HDA9
  • hdac9.S
Alternatives
anti-Human Histone Deacetylase 9 antibody for Western Blotting
Epitope
AA 503-533, C-Term
23
14
14
14
12
5
5
4
3
3
2
2
2
2
2
2
1
1
1
Reactivity
Human
128
26
21
8
5
4
4
3
2
2
2
2
1
1
1
1
Host
Rabbit
104
24
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
4
4
4
4
4
4
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
118
63
53
40
39
23
13
5
2
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen This HDAC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 503-533 AA from the C-terminal region of human HDAC9.
Clone RB2742
Isotype Ig Fraction
Specificity This HDAC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511~540 amino acids from the C-terminal region of human HDAC9.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name HDAC9 (HDAC9 Antibody Abstract)
Background Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
Synonyms: Histone deacetylase 9, HD9, HD7B
Molecular Weight 111297 DA
Gene ID 9734
UniProt Q9UKV0
Research Area Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Chromatin, Cell Structure
Pathways Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
 image for anti-Histone Deacetylase 9 (HDAC9) (AA 503-533), (C-Term) antibody (ABIN387961) Both anti-HDAC9 N-term (ABIN387960) and C-term (ABIN387961) Pab were tested by WB and...
Immunohistochemistry (IHC) image for anti-Histone Deacetylase 9 (HDAC9) (AA 503-533), (C-Term) antibody (ABIN387961) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Product cited in: Lenoir, Flosseau, Ma, Blondeau, Mai, Bassel-Duby, Ravassard, Olson, Haumaitre, Scharfmann: "Specific control of pancreatic endocrine ?- and ?-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9." in: Diabetes, Vol. 60, Issue 11, pp. 2861-71, 2011 (PubMed).

Background publications Petrie, Guidez, Howell, Healy, Waxman, Greaves, Zelent: "The histone deacetylase 9 gene encodes multiple protein isoforms." in: The Journal of biological chemistry, Vol. 278, Issue 18, pp. 16059-72, 2003 (PubMed).

David, Cardoso, Marques, Marques, Silva, Santos, Boavida: "Molecular characterization of a familial translocation implicates disruption of HDAC9 and possible position effect on TGFbeta2 in the pathogenesis of Peters' anomaly." in: Genomics, Vol. 81, Issue 5, pp. 489-503, 2003 (PubMed).

Mahlknecht, Schnittger, Will, Cicek, Hoelzer: "Chromosomal organization and localization of the human histone deacetylase 9 gene (HDAC9)." in: Biochemical and biophysical research communications, Vol. 293, Issue 1, pp. 182-91, 2002 (PubMed).

Zhou, Marks, Rifkind, Richon: "Cloning and characterization of a histone deacetylase, HDAC9." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 19, pp. 10572-7, 2001 (PubMed).

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