Cited in 1 publication.
The Rabbit Polyclonal anti-ELP3/KAT9 antibody (Clone RB14284) (ABIN387966) specifically detects ELP3/KAT9 in WB.
The antibody is reactive with Human and Mouse samples.
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This ELP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-44 amino acids from the N-terminal region of human ELP3.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Barton, Braet, Marc, Overall, Gardiner: "ELP3 localises to mitochondria and actin-rich domains at edges of HeLa cells." in: Neuroscience letters, Vol. 455, Issue 1, pp. 60-4, (2009) (PubMed).
Target
ELP3/KAT9 (ELP3)
(Elongator complex protein 3 (ELP3))
Alternative Name
ELP3
Background
Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.