ELP3/KAT9 antibody (Internal Region)

Catalog No. ABIN6261522

Product Details anti-ELP3/KAT9 Antibody

Target: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELP3/KAT9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: ELP3 Antibody detects endogenous levels of total ELP3.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ELP3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ELP3/KAT9

Target: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Alternative Name: ELP3 (ELP3 Products)

Synonyms: KAT9 antibody, 2610507P14Rik antibody, si:ch211-63o20.8 antibody, zgc:113140 antibody, elongator acetyltransferase complex subunit 3 antibody, elongator acetyltransferase complex subunit 3 L homeolog antibody, ELP3 antibody, Elp3 antibody, elp3.L antibody, elp3 antibody

Background:

Description: Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in acetylation of alpha-tubulin (PubMed:19185337). May also have a methyltransferase activity. Involved in cell migration. Involved in neurogenesis. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation.

Gene: ELP3

Molecular Weight: 62 kDa

Gene ID: 55140

UniProt: Q9H9T3