NMD3 antibody (C-Term)

Catalog No. ABIN388665

The Rabbit Polyclonal anti-NMD3 antibody (Clone RB9708) (ABIN388665) specifically detects NMD3 in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for NMD3 antibody (C-Term) (ABIN388665)

Target: NMD3 (60S Ribosomal Export Protein NMD3 (NMD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMD3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB9708

Product Details anti-NMD3 Antibody

Binding Specificity: AA 410-440, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This NMD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-440 amino acids from the C-terminal region of human NMD3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for NMD3

Target: NMD3 (60S Ribosomal Export Protein NMD3 (NMD3))

Alternative Name: NMD3

Background: It has been suggested that NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.

Molecular Weight: 57603

Gene ID: 51068

NCBI Accession: NP_057022

UniProt: Q96D46