Prohibitin antibody (C-Term)

Catalog No. ABIN389161

This Rabbit Polyclonal antibody specifically detects Prohibitin in WB. It exhibits reactivity toward Human.

Quick Overview for Prohibitin antibody (C-Term) (ABIN389161)

Target: Prohibitin (PHB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prohibitin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB10627

Product Details anti-Prohibitin Antibody

Binding Specificity: AA 182-211, C-Term

Predicted Reactivity: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PHB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from the C-terminal region of human PHB1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Prohibitin

Target: Prohibitin (PHB)

Alternative Name: PHB1

Background: Prohibitin is an evolutionarily conserved protein that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region.

Molecular Weight: 29804

Gene ID: 5245

NCBI Accession: NP_001268425, NP_001268644, NP_002625

UniProt: P35232

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling