WIF1 antibody (N-Term)

Catalog No. ABIN389184

Cited in 1 publication. The Rabbit Polyclonal anti-WIF1 antibody (Clone RB10582) (ABIN389184) specifically detects WIF1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for WIF1 antibody (N-Term) (ABIN389184)

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB10582

Product Details anti-WIF1 Antibody

Binding Specificity: AA 51-80, N-Term

Predicted Reactivity: Rat, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This WIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 amino acids from the N-terminal region of human WIF1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-WIF1 antibody (ABIN389184)

Zhou, Chen, Mashrah, Zhu, He, Hu, Xiang, Yao, Guo, Zhang: "Expression and promoter methylation of Wnt inhibitory factor-1 in the development of oral submucous fibrosis." in: Oncology reports, Vol. 34, Issue 5, pp. 2636-42, (2015) (PubMed).

Target Details for WIF1

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Alternative Name: WIF1

Background: WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 is a secreted protein, which binds WNT proteins and inhibits their activities. This protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. It may be involved in mesoderm segmentation. This protein is found to be present in fish, amphibia and mammals.

Molecular Weight: 41528

Gene ID: 11197

NCBI Accession: NP_009122

UniProt: Q9Y5W5

Pathways: WNT Signaling, Positive Regulation of fat Cell Differentiation