AHCY antibody (C-Term)

Catalog No. ABIN389202

The Rabbit Polyclonal anti-AHCY antibody (Clone RB14982) (ABIN389202) specifically detects AHCY in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for AHCY antibody (C-Term) (ABIN389202)

Target: AHCY (Adenosylhomocysteinase (AHCY))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AHCY antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14982

Product Details anti-AHCY Antibody

Binding Specificity: AA 407-432, C-Term

Predicted Reactivity: Pr

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This S adenosylhomocysteine hydrolase (ACHY) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-432 amino acids from the C-terminal region of human S adenosylhomocysteine hydrolase (ACHY).

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for AHCY

Target: AHCY (Adenosylhomocysteinase (AHCY))

Background: S-adenosylhomocysteine hydrolase (AHCY) catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family.

Molecular Weight: 47716

Gene ID: 191

NCBI Accession: NP_000678, NP_001155238

UniProt: P23526