ELP2 antibody (C-Term)

Catalog No. ABIN389412

The Rabbit Polyclonal anti-ELP2 antibody (Clone RB18010) (ABIN389412) specifically detects ELP2 in WB, FACS and IF. The antibody is reactive with Human samples.

Quick Overview for ELP2 antibody (C-Term) (ABIN389412)

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELP2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: RB18010

Product Details anti-ELP2 Antibody

Binding Specificity: AA 737-765, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ELP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-765 amino acids from the C-terminal region of human ELP2.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:100. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ELP2

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Alternative Name: ELP2

Background: ELP2 regulates the ligand-dependent activation of STAT3. The protein acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.

Molecular Weight: 92500

Gene ID: 55250

NCBI Accession: NP_001229804, NP_001229805, NP_001229806, NP_001229807, NP_001229808, NP_060725

UniProt: Q6IA86

Pathways: Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus