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Crk antibody (pSer41)

CRK Reactivity: Human DB Host: Rabbit Polyclonal RB17175 unconjugated
Catalog No. ABIN389702
  • Target See all Crk (CRK) Antibodies
    Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
    Binding Specificity
    • 22
    • 15
    • 9
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer41
    Reactivity
    • 77
    • 22
    • 15
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 69
    • 8
    Rabbit
    Clonality
    • 69
    • 8
    Polyclonal
    Conjugate
    • 40
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Crk antibody is un-conjugated
    Application
    • 62
    • 34
    • 27
    • 27
    • 15
    • 13
    • 7
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    Dot Blot (DB)
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CRK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S41 of human CRK.
    Clone
    RB17175
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CRK Primary Antibody
  • Application Notes
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
    Alternative Name
    CRK (CRK Products)
    Synonyms
    CG1587 antibody, CRK antibody, D-CRK antibody, D-Crk antibody, DCrk antibody, Dcrk antibody, Dmel\\CG1587 antibody, crk antibody, dCRK antibody, dCrk antibody, fb34h10 antibody, fc05a01 antibody, fi19g05 antibody, wu:fb34h10 antibody, wu:fc05a01 antibody, wu:fc54a04 antibody, wu:fi19g05 antibody, zgc:100936 antibody, CRKII antibody, p38 antibody, Crko antibody, crk2 antibody, crkII antibody, v-crk antibody, P38C-CRK antibody, Crk-I antibody, Crk-II antibody, Crk-III antibody, Crk3 antibody, CrkIII antibody, c-Crk antibody, Crk oncogene antibody, v-crk avian sarcoma virus CT10 oncogene homolog antibody, CRK proto-oncogene, adaptor protein antibody, v-crk avian sarcoma virus CT10 oncogene homolog L homeolog antibody, v-crk sarcoma virus CT10 oncogene homolog antibody, Crk antibody, crk antibody, CRK antibody, crk.L antibody
    Background
    CRK is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.
    Molecular Weight
    33831
    Gene ID
    1398
    NCBI Accession
    NP_005197, NP_058431
    UniProt
    P46108
    Pathways
    Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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