CLCN4 antibody (C-Term)

Catalog No. ABIN2840747

The Rabbit Polyclonal anti-CLCN4 antibody is suitable to detect CLCN4 in samples from Human. It has been validated for WB, IF and IHC (p).

Quick Overview for CLCN4 antibody (C-Term) (ABIN2840747)

Target: CLCN4 (Chloride Channel 4 (CLCN4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB0752

Product Details anti-CLCN4 Antibody

Binding Specificity: AA 663-689, C-Term

Predicted Reactivity: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CLC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 663-689 amino acids from the C-terminal region of human CLC4.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P-Leica: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CLCN4

Target: CLCN4 (Chloride Channel 4 (CLCN4))

Alternative Name: CLC4

Background: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders.

Molecular Weight: 84917

Gene ID: 1183

NCBI Accession: NP_001821

UniProt: P51793