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IL1R1 antibody (Interleukin 1 Receptor, Type I) (AA 474-503) Primary Antibody

IL1R1 Reactivity: Human WB Host: Rabbit Polyclonal RB06973 unconjugated
Catalog No. ABIN390328
$423.50
Plus shipping costs $45.00
400 μL ABIN390328
400 μL ABIN390328
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days
  • Target
    IL1R1
    Binding Specificity
    • 21
    • 18
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 474-503, C-Term
    Reactivity
    • 107
    • 54
    • 36
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 107
    • 19
    • 10
    • 5
    • 2
    • 1
    Rabbit
    Clonality
    • 106
    • 37
    Polyclonal
    Conjugate
    • 75
    • 15
    • 10
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL1R1 antibody is un-conjugated
    Application
    • 91
    • 82
    • 40
    • 37
    • 16
    • 15
    • 13
    • 13
    • 11
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This IL1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human IL1R.
    Clone
    RB06973
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:2000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    IL1R1
    Alternative Name
    IL1R (IL1R1 Antibody Abstract)
    Synonyms
    CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80, CD121a, CD121b, IL-iR, Il1r-1, interleukin 1 receptor type 1, interleukin 1 receptor, type I, IL1R1, Il1r1
    Background
    IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
    Molecular Weight
    65402
    Gene ID
    8808
    NCBI Accession
    NP_000868
    UniProt
    P14778
    Pathways
    NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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