IL1R1 antibody (Interleukin 1 Receptor, Type I) (AA 18-167)

Catalog No. ABIN5542457

Product Details anti-IL1R1 Antibody

Target: IL1R1

Binding Specificity: AA 18-167

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL1R1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)

Immunogen: Purified recombinant fragment of human IL1R1 (AA 18-167) expressed in E. Coli.

Clone: 4D2D12

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.05 % sodium azide

Storage: 4 °C,-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for IL1R1

Target: IL1R1

Alternative Name: IL1R1 (IL1R1 Antibody Abstract)

Synonyms: CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80, CD121a, CD121b, IL-iR, Il1r-1, interleukin 1 receptor type 1, interleukin 1 receptor, type I, IL1R1, Il1r1

Background: This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.,

Molecular Weight: 46.5kDa

HGNC: 154

Pathways: NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints