Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IL1R1 antibody (Interleukin 1 Receptor, Type I) (pTyr496) Primary Antibody

IL1R1 Reactivity: Human, Mouse, Rat ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN801423
$339.90
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target
    IL1R1
    Binding Specificity
    • 20
    • 19
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr496
    Reactivity
    • 107
    • 53
    • 35
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 107
    • 19
    • 10
    • 5
    • 2
    • 1
    Rabbit
    Clonality
    • 106
    • 37
    Polyclonal
    Conjugate
    • 75
    • 15
    • 10
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL1R1 antibody is un-conjugated
    Application
    • 91
    • 81
    • 40
    • 36
    • 16
    • 14
    • 12
    • 12
    • 10
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Cross-Reactivity
    Dog, Horse, Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human IL-1R1 around the phosphorylation site of Tyr496
    Isotype
    IgG
  • Application Notes
    WB 1:300-1000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C
    Expiry Date
    12 months
  • Target
    IL1R1
    Alternative Name
    IL-1R1 (IL1R1 Antibody Abstract)
    Synonyms
    CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80, CD121a, CD121b, IL-iR, Il1r-1, interleukin 1 receptor type 1, interleukin 1 receptor, type I, IL1R1, Il1r1
    Background

    Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.

    Subcellular location: Secreted, Cell membrane

    Synonyms: P8, IL1R, IL1RA, CD121A, D2S1473, IL-1R-alpha, Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, Interleukin-1 receptor type I, IL1R1, IL1RT1

    Gene ID
    3554
    UniProt
    P14778
    Pathways
    NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
You are here:
help Support