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IL1R1 antibody (pTyr496)

IL1R1 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, ICC, IHC (p), IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN801423
  • Target See all IL1R1 Antibodies
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Binding Specificity
    • 27
    • 17
    • 16
    • 8
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr496
    Reactivity
    • 118
    • 62
    • 52
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 112
    • 13
    • 9
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 119
    • 19
    Polyclonal
    Conjugate
    • 58
    • 16
    • 11
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This IL1R1 antibody is un-conjugated
    Application
    • 121
    • 63
    • 44
    • 39
    • 15
    • 14
    • 12
    • 12
    • 10
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human IL-1R1 around the phosphorylation site of Tyr496
    Isotype
    IgG
    Top Product
    Discover our top product IL1R1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Alternative Name
    IL-1R1 (IL1R1 Products)
    Synonyms
    CD121A antibody, D2S1473 antibody, IL-1R-alpha antibody, IL1R antibody, IL1RA antibody, P80 antibody, CD121a antibody, CD121b antibody, IL-iR antibody, Il1r-1 antibody, DER4 antibody, Fit-1 antibody, Ly84 antibody, ST2L antibody, St2 antibody, St2-rs1 antibody, T1 antibody, T1/ST2 antibody, interleukin 1 receptor type 1 antibody, interleukin 1 receptor, type I antibody, interleukin 1 receptor-like 1 antibody, IL1R1 antibody, Il1r1 antibody, Il1rl1 antibody
    Background

    Synonyms: P8, IL1R, IL1RA, CD121A, D2S1473, IL-1R-alpha, Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, Interleukin-1 receptor type I, IL1R1, IL1RT1

    Background: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.

    Gene ID
    3554
    UniProt
    P14778
    Pathways
    NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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