Fibrinogen beta Chain antibody (N-Term)

Catalog No. ABIN390413

Product Details anti-Fibrinogen beta Chain Antibody

Target: Fibrinogen beta Chain (FGB)

Binding Specificity: AA 29-58, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrinogen beta Chain antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This FIBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human FIBB.

Clone: RB19512

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Alternative Name: FIBB (FGB Products)

Synonyms: FGB antibody, 2510049G14Rik antibody, DKFZp470D0312 antibody, LOC100223598 antibody, fibrinogen antibody, Ab1-216 antibody, Ac1-581 antibody, wu:fa55c11 antibody, zgc:77116 antibody, fgb antibody, fibrinogen beta chain antibody, fibrinogen beta chain L homeolog antibody, FGB antibody, Fgb antibody, fgb antibody, fgb.L antibody

Background: FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Molecular Weight: 55928

Gene ID: 2244

NCBI Accession: NP_001171670, NP_005132

UniProt: P02675