Endonuclease G antibody (C-Term)
Quick Overview for Endonuclease G antibody (C-Term) (ABIN390490)
Target
See all Endonuclease G (ENDOG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 188-217, C-Term
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Predicted Reactivity
- B
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This ENDOG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the C-terminal region of human ENDOG.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 6 months
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- Endonuclease G (ENDOG)
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Alternative Name
- ENDOG
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Background
- ENDOG is a nuclear encoded endonuclease that is localized in the mitochondrion. The protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
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Molecular Weight
- 32620
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Gene ID
- 2021
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NCBI Accession
- NP_004426
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UniProt
- Q14249
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Pathways
- Apoptosis
Target
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