Aminomethyltransferase antibody (N-Term)

Catalog No. ABIN390700

This Rabbit Polyclonal antibody specifically detects Aminomethyltransferase in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Aminomethyltransferase antibody (N-Term) (ABIN390700)

Target: Aminomethyltransferase (AMT)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aminomethyltransferase antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19704

Product Details anti-Aminomethyltransferase Antibody

Binding Specificity: AA 19-45, N-Term

Predicted Reactivity: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This AMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human AMT.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Aminomethyltransferase

Target: Aminomethyltransferase (AMT)

Alternative Name: AMT

Background: The enzyme system for cleavage of glycine (glycine cleavage system, EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase, MIM 238300), H protein (a lipoic acid-containing protein, MIM 238330), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase, MIM 238331). Glycine encephalopathy (GCE, MIM 605899) may be due to a defect in any one of these enzymes.

Molecular Weight: 43946

Gene ID: 275

NCBI Accession: NP_000472, NP_001158182, NP_001158183, NP_001158184

UniProt: P48728