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HMGCS2 antibody (C-Term)
HMGCS2
Reactivity: Human
WB, FACS, IHC (p)
Host: Rabbit
Polyclonal
RB19373
unconjugated
Product Details anti-HMGCS2 Antibody
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Target
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HMGCS2
(3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))
Binding Specificity
All epitopes for HMGCS2 antibodies
AA 478-508, C-Term
Reactivity
All reactivities for HMGCS2 antibodies
Human
Host
All hosts for HMGCS2 antibodies
Rabbit
Clonality
All clonalities for HMGCS2 antibodies
Polyclonal
Conjugate
All conjugates for HMGCS2 antibodies
This HMGCS2 antibody is un-conjugated
Application
All applications for HMGCS2 antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This HMGCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-508 amino acids from the C-terminal region of human HMGCS2.
Clone
RB19373
Isotype
Ig Fraction
Top Product
Discover our top product HMGCS2 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-HMGCS2 antibody (ABIN390764)
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Huang, Li, Wang, Zhang, Yan, Li, Xing, Wu, Hu, Jia, Lin, Dang, Song, Gao, Zhang : "Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress. " in: Cell research , Vol. 26 , Issue 10 , pp. 1112-1130 , (2017 ) (PubMed ).
Target Details for HMGCS2
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Target
HMGCS2
(3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))
Alternative Name
HMGCS2 (HMGCS2 Products )
Synonyms
1300002P16 antibody, mHS antibody, DDBDRAFT_0219349 antibody, DDBDRAFT_0219924 antibody, DDB_0219349 antibody, DDB_0219924 antibody, Hmgcs1 antibody, Mt3h3mg antibody, hmgCoA antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 2 antibody, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 antibody, hydroxymethylglutaryl-CoA synthase antibody, hydroxymethylglutaryl-coa synthase antibody, 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 antibody, HMGCS2 antibody, Hmgcs2 antibody, mvaS antibody, CNC05080 antibody, HMCS1 antibody, hgsA antibody, MFER_RS00425 antibody, LOC100285783 antibody, ECU10_0510 antibody, Eint_100450 antibody
Background
HMGCS2 belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting.
Molecular Weight
56635
Gene ID
3158
NCBI Accession
NP_001159579 , NP_005509
UniProt
P54868
Pathways
Response to Growth Hormone Stimulus , Cellular Response to Molecule of Bacterial Origin , Regulation of Lipid Metabolism by PPARalpha
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