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PKC theta antibody (C-Term)

PRKCQ Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB01242 unconjugated
Catalog No. ABIN391017
  • Target See all PKC theta (PRKCQ) Antibodies
    PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
    Binding Specificity
    • 30
    • 28
    • 15
    • 12
    • 11
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 318-348, C-Term
    Reactivity
    • 93
    • 66
    • 54
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 120
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 122
    • 3
    Polyclonal
    Conjugate
    • 59
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This PKC theta antibody is un-conjugated
    Application
    • 106
    • 47
    • 40
    • 40
    • 38
    • 23
    • 11
    • 10
    • 5
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PKC theta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-348 amino acids from the C-terminal region of human PKC theta.
    Clone
    RB01242
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PRKCQ Primary Antibody
  • Application Notes
    WB: 1:2000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
    Alternative Name
    PKC theta (PRKCQ Products)
    Synonyms
    PRKCT antibody, nPKC-theta antibody, A130035A12Rik antibody, AW494342 antibody, PKC-0 antibody, PKC-theta antibody, PKCtheta antibody, Pkcq antibody, protein kinase C theta antibody, protein kinase C eta antibody, protein kinase C, theta antibody, PRKCQ antibody, PRKCH antibody, Prkcq antibody
    Background
    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. PKC theta is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.
    Molecular Weight
    81865
    Gene ID
    5588
    NCBI Accession
    NP_001229342, NP_006248
    UniProt
    Q04759
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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