CKM antibody (C-Term)

Catalog No. ABIN391096

This Rabbit Polyclonal antibody specifically detects CKM in WB, FACS and IHC (p). It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for CKM antibody (C-Term) (ABIN391096)

Target: CKM (Creatine Kinase, Muscle (CKM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CKM antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB5382

Product Details anti-CKM Antibody

Binding Specificity: AA 283-313, C-Term

Predicted Reactivity: B, Pig, Rb

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CKM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-313 amino acids from the C-terminal region of human CKM.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-CKM antibody (ABIN391096)

Yang, Fann, Chang, Tai, Jiang, Kao: "Regulation of sodium-calcium exchanger activity by creatine kinase under energy-compromised conditions." in: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 28275-85, (2010) (PubMed).

Target Details for CKM

Target: CKM (Creatine Kinase, Muscle (CKM))

Alternative Name: CKM

Background: Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. The CKM isoform, predominant in skeletal muscle and heart tissue, is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. CKM reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.

Molecular Weight: 43101

Gene ID: 1158

NCBI Accession: NP_001815

UniProt: P06732