DAP Kinase 1 antibody (C-Term)

Catalog No. ABIN391321

This Rabbit Polyclonal antibody specifically detects DAP Kinase 1 in WB, IF and IHC (p). It exhibits reactivity toward Human and Mouseand has been mentioned in 1 publication.

Quick Overview for DAP Kinase 1 antibody (C-Term) (ABIN391321)

Target: DAP Kinase 1 (DAPK1) (Death-Associated Protein Kinase 1 (DAPK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAP Kinase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB3033

Product Details anti-DAP Kinase 1 Antibody

Binding Specificity: AA 1360-1389, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This DAPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1360-1389 amino acids from the C-terminal region of human DAPK1.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-DAP Kinase 1 antibody (ABIN391321)

Bai, Zhang, Hu, Liu, Wang, Li, Lin, Zhang, Sun, Du, Song: "Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK." in: Oncotarget, Vol. 7, Issue 28, pp. 44129-44141, (2018) (PubMed).

Target Details for DAP Kinase 1

Target: DAP Kinase 1 (DAPK1) (Death-Associated Protein Kinase 1 (DAPK1))

Alternative Name: DAP Kinase 1 (DAPK1)

Background: Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death (apoptosis). DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate.

Molecular Weight: 160046

Gene ID: 1612

NCBI Accession: NP_004929

UniProt: P53355

Pathways: MAPK Signaling, Interferon-gamma Pathway