CPN1 antibody (N-Term)

Catalog No. ABIN391509

Product Details anti-CPN1 Antibody

Target: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Binding Specificity: AA 52-81, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPN1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human CPN1.

Clone: RB19020

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CPN1

Target: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Alternative Name: CPN1 (CPN1 Products)

Synonyms: CPN antibody, SCPN antibody, Cpn antibody, cb1037 antibody, fa99g08 antibody, wu:fa99g08 antibody, zgc:77485 antibody, cpn antibody, scpn antibody, 0610011F20Rik antibody, carboxypeptidase N subunit 1 antibody, carboxypeptidase N, polypeptide 1 antibody, carboxypeptidase N subunit 1 S homeolog antibody, CPN1 antibody, Cpn1 antibody, cpn1 antibody, cpn1.S antibody

Background: CPN1 is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The protein is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This protein is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits.

Molecular Weight: 52286

Gene ID: 1369

NCBI Accession: NP_001299

UniProt: P15169

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process