FBP1 antibody (N-Term)

Catalog No. ABIN391576

This Rabbit Polyclonal antibody specifically detects FBP1 in WB and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for FBP1 antibody (N-Term) (ABIN391576)

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19298

Product Details anti-FBP1 Antibody

Binding Specificity: AA 1-31, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This FBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-31 amino acids from the N-terminal region of human FBP1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-FBP1 antibody (ABIN391576)

Liu, Quek, Sultani, Turner: "Epithelial-mesenchymal transition induction is associated with augmented glucose uptake and lactate production in pancreatic ductal adenocarcinoma." in: Cancer & metabolism, Vol. 4, pp. 19, (2016) (PubMed).

Target Details for FBP1

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Alternative Name: FBP1

Background: Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.

Molecular Weight: 36842

Gene ID: 2203

NCBI Accession: NP_000498, NP_001121100

UniProt: P09467

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport