Annexin A2 antibody (N-Term)

Catalog No. ABIN391619

The Rabbit Polyclonal anti-Annexin A2 antibody has been validated for WB and IHC (p). It is suitable to detect Annexin A2 in samples from Human and Mouse. There are 2+ publications available.

Quick Overview for Annexin A2 antibody (N-Term) (ABIN391619)

Target: Annexin A2 (ANXA2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB15421

Product Details anti-Annexin A2 Antibody

Binding Specificity: AA 19-49, N-Term

Predicted Reactivity: B, Pig, Rat, Sh

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ANXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-49 amino acids from the N-terminal region of human ANXA2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Annexin A2 antibody (ABIN391619)

Li, Syrovets, Simmet, Ding, Xu, Chen, Zhu, Gao: "Plasmin induces intercellular adhesion molecule 1 expression in human endothelial cells via nuclear factor-?B/mitogen-activated protein kinases-dependent pathways." in: Experimental biology and medicine (Maywood, N.J.), Vol. 238, Issue 2, pp. 176-86, (2013) (PubMed).

Li, Ke, Zhang, Shen, Xu, Wang, Yu, Leng, Wang: "Plasmin plays an essential role in amplification of psoriasiform skin inflammation in mice." in: PLoS ONE, Vol. 6, Issue 2, pp. e16483, (2011) (PubMed).

Target Details for Annexin A2

Target: Annexin A2 (ANXA2)

Alternative Name: ANXA2

Background: ANXA2 is a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption.

Molecular Weight: 38604

Gene ID: 302

NCBI Accession: NP_001002857, NP_001002858, NP_001129487, NP_004030

UniProt: P07355

Pathways: S100 Proteins