Annexin A2 antibody (pSer26)

Catalog No. ABIN6255139

Product Details anti-Annexin A2 Antibody

Target: Annexin A2 (ANXA2)

Binding Specificity: pSer26

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Phospho-Annexin A2 (Ser26) Antibody detects endogenous levels of Annexin A2 only when phosphorylated at Ser26.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human Annexin A2 around the phosphorylation site of Ser26.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Annexin A2

Target: Annexin A2 (ANXA2)

Alternative Name: ANXA2 (ANXA2 Products)

Synonyms: ANX2 antibody, ANX2L4 antibody, CAL1H antibody, LIP2 antibody, LPC2 antibody, LPC2D antibody, P36 antibody, PAP-IV antibody, AW215814 antibody, Cal1h antibody, p36 antibody, anx2 antibody, lip2 antibody, lpc2 antibody, cal1h antibody, lpc2d antibody, pap-i antibody, anx2l4 antibody, MGC76145 antibody, ANXA2 antibody, anxa2 antibody, anxa2-a antibody, anxa2-b antibody, annexin A2 antibody, annexin A2 S homeolog antibody, ANXA2 antibody, Anxa2 antibody, anxa2 antibody, anxa2.S antibody

Background:

Description: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640).

Gene: ANXA2

Molecular Weight: 37 kDa

Gene ID: 302

UniProt: P07355

Pathways: S100 Proteins