Thrombopoietin antibody (AA 243-273)
Quick Overview for Thrombopoietin antibody (AA 243-273) (ABIN391803)
Target
See all Thrombopoietin (THPO) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 243-273
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This Thrombopoietin (TPO) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-273 amino acids from the Central region of human Thrombopoietin (TPO).
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 6 months
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- Thrombopoietin (THPO)
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Alternative Name
- Thrombopoietin (TPO)
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Background
- Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. It is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.
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Molecular Weight
- 37823
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Gene ID
- 7066
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NCBI Accession
- NP_000451, NP_001171068, NP_001171069
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UniProt
- P40225
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Pathways
- JAK-STAT Signaling, Hormone Activity
Target
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