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EARS2 antibody (C-Term)

EARS2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB14808 unconjugated
Catalog No. ABIN391828
  • Target See all EARS2 Antibodies
    EARS2 (Glutamyl-tRNA Synthetase 2 Mitochondrial (EARS2))
    Binding Specificity
    • 5
    • 2
    • 2
    • 1
    • 1
    AA 495-523, C-Term
    Reactivity
    • 12
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 11
    • 2
    Rabbit
    Clonality
    • 13
    Polyclonal
    Conjugate
    • 9
    • 2
    • 1
    • 1
    This EARS2 antibody is un-conjugated
    Application
    • 7
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This EARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human EARS2.
    Clone
    RB14808
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Boczonadi, Smith, Pyle, Gomez-Duran, Schara, Tulinius, Chinnery, Horvath: "Altered 2-thiouridylation impairs mitochondrial translation in reversible infantile respiratory chain deficiency." in: Human molecular genetics, Vol. 22, Issue 22, pp. 4602-15, (2013) (PubMed).

  • Target
    EARS2 (Glutamyl-tRNA Synthetase 2 Mitochondrial (EARS2))
    Alternative Name
    EARS2 (EARS2 Products)
    Synonyms
    mse1 antibody, 3230401I01Rik antibody, AL024049 antibody, mKIAA1970 antibody, COXPD12 antibody, MSE1 antibody, RGD1307904 antibody, ears2 antibody, glutamyl-tRNA synthetase 2, mitochondrial antibody, zgc:153247 antibody, EARS2 antibody, ears2 antibody, Ears2 antibody, zgc:153247 antibody
    Background
    Glutamyl-tRNA synthetase (GluRS or EARS2) a class I aminoacyl-tRNA synthetase (aaRS), is primarily responsible for the glutamylation of tRNAGlu. It is part of the ?minimal set?of seventeen aaRSs found in every living organism and its presence is essential for the viability of cells.
    Molecular Weight
    58689
    Gene ID
    124454
    NCBI Accession
    NP_001077083
    UniProt
    Q5JPH6
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