LUM antibody (N-Term)

Catalog No. ABIN391881

This anti-LUM antibody is a Rabbit Polyclonal antibody detecting LUM in WB, FACS and IHC (p). Suitable for Human and Mouse. This Primary Antibody has been cited in 1 publication.

Quick Overview for LUM antibody (N-Term) (ABIN391881)

Target: LUM (Lumican (LUM))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LUM antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB18422

Product Details anti-LUM Antibody

Binding Specificity: AA 64-91, N-Term

Predicted Reactivity: Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This LUM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-91 amino acids from the N-terminal region of human LUM.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-LUM antibody (ABIN391881)

Xia, Hong, Ye, Wang, Chen, Liu: "Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients." in: Journal of proteomics, Vol. 84, pp. 78-91, (2013) (PubMed).

Target Details for LUM

Target: LUM (Lumican (LUM))

Alternative Name: LUM

Background: LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

Molecular Weight: 38429

Gene ID: 4060

NCBI Accession: NP_002336

UniProt: P51884

Pathways: Glycosaminoglycan Metabolic Process