MPST antibody (C-Term)

Catalog No. ABIN392001

This anti-MPST antibody is a Rabbit Polyclonal antibody detecting MPST in WB and FACS. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for MPST antibody (C-Term) (ABIN392001)

Target: MPST (Mercaptopyruvate Sulfurtransferase (MPST))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPST antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB18649

Product Details anti-MPST Antibody

Binding Specificity: AA 269-297, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MPST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-297 amino acids from the C-terminal region of human MPST.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-MPST antibody (ABIN392001)

Akahoshi, Kamata, Kubota, Hishiki, Nagahata, Matsuura, Yamazaki, Yoshida, Yamada, Ishizaki, Suematsu, Kasahara, Ishii: "Neutral aminoaciduria in cystathionine ?-synthase-deficient mice; an animal model of homocystinuria." in: American journal of physiology. Renal physiology, Vol. 306, Issue 12, pp. F1462-76, (2014) (PubMed).

Target Details for MPST

Target: MPST (Mercaptopyruvate Sulfurtransferase (MPST))

Alternative Name: MPST

Background: MPST catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU).

Molecular Weight: 33178

Gene ID: 4357

NCBI Accession: NP_001013454, NP_001123989, NP_066949

UniProt: P25325