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DDR2 antibody (AA 290-320)

DDR2 Reactivity: Human WB Host: Rabbit Polyclonal RB01473 unconjugated
Catalog No. ABIN392068
  • Target See all DDR2 Antibodies
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    Binding Specificity
    • 9
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 290-320
    Reactivity
    • 35
    • 25
    • 2
    • 1
    Human
    Host
    • 41
    • 7
    Rabbit
    Clonality
    • 41
    • 7
    Polyclonal
    Conjugate
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DDR2 antibody is un-conjugated
    Application
    • 34
    • 28
    • 21
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This DDR2 (TYRO10) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from human DDR2 (TYRO10).
    Clone
    RB01473
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DDR2 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    Alternative Name
    DDR2 (TYRO10) (DDR2 Products)
    Synonyms
    MIG20a antibody, NTRKR3 antibody, TKT antibody, TYRO10 antibody, AW495251 antibody, Ntrkr3 antibody, tyro10 antibody, DDR2 antibody, Tyro10 antibody, ddr2 antibody, si:ch211-193c2.1 antibody, discoidin domain receptor tyrosine kinase 2 antibody, discoidin domain receptor family, member 2 antibody, discoidin domain receptor family, member 2, like antibody, DDR2 antibody, Ddr2 antibody, ddr2l antibody
    Background
    Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane and cytoplasmic regions. There are several subclasses of RTKs and TYRO10 belongs to a novel subclass. The deduced amino acid sequence of TYRO10 has a unique extracellular region encompassing a factor VIII-like domain, not previously described for RTKs.
    Molecular Weight
    96736
    Gene ID
    4921
    NCBI Accession
    NP_001014796, NP_006173
    UniProt
    Q16832
    Pathways
    RTK Signaling
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