Amphiregulin antibody (C-Term)

Catalog No. ABIN392202

This anti-Amphiregulin antibody is a Rabbit Polyclonal antibody detecting Amphiregulin in WB and IHC (p). Suitable for Human.

Quick Overview for Amphiregulin antibody (C-Term) (ABIN392202)

Target: Amphiregulin (AREG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Amphiregulin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14426

Product Details anti-Amphiregulin Antibody

Binding Specificity: AA 222-252, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This AREG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-252 amino acids from the C-terminal region of human AREG.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Amphiregulin

Target: Amphiregulin (AREG)

Alternative Name: AREG

Background: AREG is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This protein is associated with a psoriasis-like skin phenotype.

Molecular Weight: 27895

Gene ID: 374

NCBI Accession: NP_001648

UniProt: P15514

Pathways: RTK Signaling, EGFR Signaling Pathway