MAP3K14 antibody (AA 119-148)

Catalog No. ABIN392496

Product Details anti-MAP3K14 Antibody

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Binding Specificity: AA 119-148

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human NIK.

Clone: RB3337

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MAP3K14

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Alternative Name: NIK (MAP3K14 Products)

Synonyms: FTDCR1B antibody, HS antibody, HSNIK antibody, NIK antibody, F23F1.4 antibody, F23F1_4 antibody, mitogen-activated protein kinase kinase kinase 14 antibody, Nik antibody, aly antibody, mitogen-activated protein kinase kinase kinase 14 antibody, MAP3K14 antibody, Map3k14 antibody, MAPKKK14 antibody

Background: NIK (mitogen-activated protein kinase kinase kinase 14), a member of the Ser/Thr protein kinase family, binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Molecular Weight: 104042

Gene ID: 9020

NCBI Accession: NP_003945

UniProt: Q99558

Pathways: NF-kappaB Signaling, TCR Signaling