TNIK antibody (N-Term)

Catalog No. ABIN392499

This anti-TNIK antibody is a Rabbit Polyclonal antibody detecting TNIK in WB and IHC (p). Suitable for Human and Rat. This Primary Antibody has been cited in 2+ publications.

Quick Overview for TNIK antibody (N-Term) (ABIN392499)

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB3388

Product Details anti-TNIK Antibody

Binding Specificity: AA 1-30, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This TNIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TNIK.

Isotype: Ig Fraction

Application Details

Application Notes: IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-TNIK antibody (ABIN392499)

Zhang, Jiang, Qin, Su, Cao, Wang: "TNIK serves as a novel biomarker associated with poor prognosis in patients with pancreatic cancer." in: Tumour biology, (2015) (PubMed).

Wang, Charych, Pulito, Lee, Graziane, Crozier, Revilla-Sanchez, Kelly, Dunlop, Murdoch, Taylor, Xie, Pausch, Hayashi-Takagi, Ishizuka, Seshadri, Bates, Kariya, Sawa, Weinberg, Moss, Houslay, Yan et al.: "The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. ..." in: Molecular psychiatry, Vol. 16, Issue 10, pp. 1006-23, (2011) (PubMed).

Target Details for TNIK

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Alternative Name: TNIK

Background: Germinal center kinases (GCKs), such as TNIK, are characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function (Fu et al., 1999 [PubMed 10521462]).[supplied by OMIM]

Molecular Weight: 154943

Gene ID: 23043

NCBI Accession: NP_001155032, NP_001155033, NP_001155034, NP_001155035, NP_001155036, NP_001155037, NP_001155038, NP_055843

UniProt: Q9UKE5