MARK2 antibody (C-Term)

Catalog No. ABIN392538

Cited in 1 publication. The Rabbit Polyclonal anti-MARK2 antibody (Clone RB2527-2528) (ABIN392538) specifically detects MARK2 in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for MARK2 antibody (C-Term) (ABIN392538)

Target: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB2527-2528

Product Details anti-MARK2 Antibody

Binding Specificity: AA 600-630, C-Term

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MARK2 (EMK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 600-630 amino acids from the C-terminal region of human MARK2 (EMK).

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-MARK2 antibody (ABIN392538)

Yoshiike, Yamashita, Mizoroki, Maeda, Murayama, Kimura, Sahara, Soeda, Takashima: "Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes." in: Aging cell, Vol. 11, Issue 1, pp. 51-62, (2012) (PubMed).

Target Details for MARK2

Target: MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

Alternative Name: MARK2 (EMK)

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Molecular Weight: 87911

Gene ID: 2011

NCBI Accession: NP_001034558, NP_001156768, NP_001156769, NP_004945, NP_059672

UniProt: Q7KZI7

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection