CD41, CD61 antibody
Quick Overview for CD41, CD61 antibody (ABIN393089)
Target
See all CD41, CD61 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Reacts with CD41/CD61 complex (bovine), one of the earliest markers of the megakaryocytic lineage. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, vitronectin, thrombin and mediates platelets aggregation. CD41/CD61 is expressed only by platelets and megakaryocytes, the complex may be absent or strongly reduced in Glanzmann's thrombasthenia (GT)
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Purification
- Protein A purified
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Immunogen
- Bovine platelets.
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Isotype
- IgG2
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Bovine
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 15 mM sodium azide, approx, pH 7.4.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- avoid freeze thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- CD41, CD61 (CD41,CD61)
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Background
- This antibody detects: CD41 + CD61
Target
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