Glucose-6-Phosphate Dehydrogenase antibody (AA 35-506)
Quick Overview for Glucose-6-Phosphate Dehydrogenase antibody (AA 35-506) (ABIN400862)
Target
See all Glucose-6-Phosphate Dehydrogenase (G6PD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 35-506
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Specificity
- The antibody recognizes human G6PD. Other species not tested.
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Characteristics
- Synonyms: Glucose-6-phosphate 1-dehydrogenase, Glucose-6-P-Dehydrogenase
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Purification
- Protein-G affinity chromatography
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Immunogen
- Recombinant human G6PD (35-506 aa) purified from E. coli
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Isotype
- IgG2b
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Application Notes
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ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on Paraffin Sections (5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- Glucose-6-Phosphate Dehydrogenase (G6PD)
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Alternative Name
- G6PD
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Background
- Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells by maintaining the level of NADPH. G6PD converts glucose-6-phosphate into 6-phosphoglucono-δ-lactone and simultaneously produce NADPH. The NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. G6PD deficiency cause acute hemolytic anemia.Synonyms: Glucose-6-P-Dehydrogenase, Glucose-6-phosphate 1-dehydrogenase
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Gene ID
- 2539
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UniProt
- P11413
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Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
Target
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