TMBIM1 antibody (N-Term)

Catalog No. ABIN401050

This Rabbit Polyclonal antibody specifically detects TMBIM1 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for TMBIM1 antibody (N-Term) (ABIN401050)

Target: TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMBIM1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TMBIM1 Antibody

Binding Specificity: N-Term

Specificity: This antibody is specific for TMBIM1 protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: Recombinant protein corresponding to the amino terminus of human TMBIM1 protein

Isotype: IgG

Application Details

Application Notes: ELISA: 1/10,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.2 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for TMBIM1

Target: TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))

Alternative Name: TMBIM1 / RECS1

Background: TMBIM1 (Transmembrane BAX inhibitor motifcontaining protein 1) is a member of the 7 TMS (7 transmembrane domains) family of receptors known to mediate the activation of various transcription factors. TMBIM1 is identified as a novel modulator of NF-kappaB activation. A drosophila homolog of this protein (dNMDA1 with 40 % homology to hTMBIM1) is reported to be unregulated during aging and oxidative stress.Synonyms: PP1201, PSEC0158, Protein RECS1 homolog, Transmembrane BAX inhibitor motif-containing protein 1

Gene ID: 64114

NCBI Accession: NP_071435

UniProt: Q969X1