PIN1 antibody (Internal Region)

Catalog No. ABIN401395

This Rabbit Polyclonal antibody specifically detects PIN1 in WB and EIA. It exhibits reactivity toward Human, Mouse, Rat, Monkey, Cow and Dog.

Quick Overview for PIN1 antibody (Internal Region) (ABIN401395)

Target: PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))

Reactivity: Human, Mouse, Rat, Monkey, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIN1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PIN1 Antibody

Binding Specificity: Internal Region

Specificity: This antibody is directed against Pin1.

Cross-Reactivity (Details): Species reactivity (expected):Canine, Bovine, Monkey, Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding to an internal sequence of human Pin1

Isotype: IgG

Application Details

Application Notes: ELISA: 1/2,500 - 1/10,000. Western Blot: 1/500 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.2 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for PIN1

Target: PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))

Alternative Name: PIN1

Background: Pin1 (peptidylprolyl cis/trans isomerase NIMA-interacting 1 protein) is an essential peptidylprolyl isomerase that regulates mitosis, presumably by interacting with NIMA and attenuating its mitosispromoting activity. Pin1 displays a preference for an acidic residue N-terminal to the isomerized proline bond and also catalyzes pSer/Thr-Pro cis/trans isomerizations. Pin1 shows a nuclear localization.Synonyms: PIN-1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1

Gene ID: 5300

NCBI Accession: NP_006212

UniProt: Q13526