NOS1 antibody (AA 850-854)

Catalog No. ABIN401625

The Rabbit Polyclonal anti-NOS1 antibody is suitable to detect NOS1 in samples from Human, Mouse and Rat. It has been validated for IF.

Quick Overview for NOS1 antibody (AA 850-854) (ABIN401625)

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOS1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-NOS1 Antibody

Binding Specificity: AA 850-854

Specificity: This antibody detects endogenous levels of total nNOS protein.

Purification: Affinity Chromatography

Immunogen: Synthetic Peptide KLH conjugated corresponding to a sequence around amino acids 850-854 (F-N-SP-V-S) derived from Human nNOS.

Application Details

Application Notes: Immunofluorescence: 1/100 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for NOS1

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Alternative Name: NOS1

Background: NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti-tumor and anti-pathogenic activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS), induciblr NOS (iNOS) or macrophage NOS (mNOS), and endothelial NOS (eNOS).Synonyms: Constitutive NOS, NC-NOS, NOS type I, Neuronal NOS, Nitric Oxide Synthase, bNOS, nNOS

Gene ID: 4842

NCBI Accession: NP_000611

UniProt: P29475

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction