APOE antibody

Catalog No. ABIN452451

The Mouse Monoclonal anti-APOE antibody (Clone IB5-E1) (ABIN452451) specifically detects APOE in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for APOE antibody (ABIN452451)

Target: APOE (Apolipoprotein E (APOE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This APOE antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: IB5-E1

Product Details anti-APOE Antibody

Specificity: This antibody reacts with all isoforms E2, E3, E4 of Human Apolipoprotein E (ApoE). The antibody detects a 38 kDa band in Western Blotting.

Characteristics: Synonyms: ApoE, Apo-E

Purification: Affinity Chromatography on Protein G

Immunogen: Human apolipoprotein E

Isotype: IgG1

Application Details

Application Notes: ELISA. Western Blot: 1/200 with PBS, pH 7.4.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in 1 mL distilled water

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for APOE

Target: APOE (Apolipoprotein E (APOE))

Alternative Name: Apolipoprotein E (Apo E)

Background: Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.Synonyms: Apo-E, ApoE

Gene ID: 348

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism