FX antibody, FXA antibody, Cf10 antibody, fX antibody, fi12c10 antibody, wu:fi12c10 antibody, F10 antibody, f10 antibody, coagulation factor X antibody, Coagulation factor X antibody, coagulation factor 10 L homeolog antibody, F10 antibody, f10 antibody, CpipJ_CPIJ012712 antibody, CpipJ_CPIJ014863 antibody, CpipJ_CPIJ016937 antibody, CpipJ_CPIJ017791 antibody, fa10 antibody, f10.L antibody
Background
Factor X is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a haemorrhagic condition of variable severity.Synonyms: Stuart factor, Stuart-Prower factor